Lots of guys with trucks are doing a shackle reversal with super duty springs. If I remember right b and v code springs. Precision Metal Fab(PMF) makes a very nice kit for f250/350. I was about to do it to my truck but it lifts its 2 inches and I did not want to mess with my fifth wheel ride height.
Rot box mentioned upgrading the turbo housing. The vans have a smaller turbo housing then the trucks do. If you do decide to "chip" it go with a custom tuner not just Banks or Edge. I had Power Hungry Performance on my truck when it was stock. Tunes were good, no smoke, good shift points. I then installed 160 cc injectors. Had my chip reburned with TW tunes. Smoked bad, EGTS were sky high. I think it lasted 3 days. I am currently running tunes from Gearhead. No smoke.
Trans is going to be a E4od. Plan on rebuilding it. Pretty weak in stock form. Are you sure the rear axle is a 60? Most Fords used a Sterling 10.25.
Maintenance things to be aware of. Replace the fuel filter. I have to change every oil change. Remove the fuel pressure regulator screen and clean it. 7.3s are hard on engine oil due to the way the injectors are fired. I change mine every 4k miles.