I've been running a set of 37" MTR's on my 4Runner for about 3 years - 22RE and 5.29 gears. Some limited street mileage and alot of trail. They are still 3/4 tread, and the stock Toyota axles have held up to them pretty well (only broken 2 stock birfields in 3 years). They wear well on the road, especially as light as the Toyota is. They have reasonably strong sidewalls - I have yet to puncture one. And after having both 35's and 37's I would definitely say go with the 37's - they do make a difference. I would love a set of Krawlers...maybe when the MTR's are worn out. I had some 35" SSR's before the MTR's - I like the MTR's much better, they are hands-down a better street and wheelin' tire IMHO.