Search around here I have a few posts a mile long with my experience with them.
The PMD/FSD isolator from Heath (and only Heath) is a must have upgrade that would be on the top of my list. If you haul heavy get the 97-current dual t-stat housing and higher gpm water pump (the water pump is available at any auto parts store) or you
will melt the engine from the inside out. Check the harmonic balancer on the front of the engine for cracking where the rubber meets the steel. When these come apart it takes the crankshaft out with it. Get familiar with how to change the fuel filter. You can troubleshoot a faulty lift pump this way if you know what to look for. The OPS (oil pressure switch) are known to fail which cuts power to the lift pump causing hard starts and power loss at higher rpms. Its a $20 part--worth keeping a spare.
As for power 4.10 gears aren't a deal breaker but see if it has them they definitely help. A 3" free flowing down-pipe (the stock piece is kinked off horribly), a #9 resistor for the injector pump (get with Heath on that one also) and removing the snorkel between the air box and fender will make a worthwhile difference in power and lower egt's. If it's the heavy gvw 3/4 ton you'll gain an "F" vin engine and a NV4500 trans and that package does well for what they are once they're uncorked. If its a light 3/4 ton they should still have the NV4500 however they will have an "S" vin with a different pump calibration and some other restrictions on the engine netting less horsepower/torque. I could pull on my brothers 454 with my F-vin in the canyon with similar loads to give you an idea on power. A freind has an S-vin K2500 and it feels like a small block 350 under load :-\
Some years are better than others in terms of reliability. My brother had a 95 with 550K original miles before a rod let loose