I was contemplating getting a set for my current rig, but I saw a few reviews on discount tire's website that made me second-guess myself. There were several reviews on Discounttire.com that mentioned a weird shimmy/wobble at 50 mph when they're worn a bit (10k miles). I haven't met anyone in person with this problem, but I read 3 or 4 people with this issue. They said they rotated their tires religiously and tried to balance it out, but it was still there. DIscount's website actually has a lot of good reviews from people who tow, wheel, dd, etc. Aside from those few reviews (and every tire's going to have a few bad reviews), everything else I've heard about them has been great. It seems like you need to air them down a bit more than your typical tire to get them to bulge, but that's no biggie.
I'd run 'em if the price was right. If you complete the treadlightly online course, they'll give you a $100 off coupon for goodyear tires. Pretty cool deal there.